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Grin2a - glutamate ionotropic receptor NMDA type subunit 2A

Alias:
NR2A
GluN2A
NMDAR2A
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括酶结合活性;谷氨酸结合活性;以及配体门控离子通道活性。参与阳离子通道活性和细胞外谷氨酸门控离子通道活性。涉及几个过程,包括细胞对金属离子的反应;中枢神经系统发育;以及化学突触传递的调节。位于几个细胞成分中,包括树突棘;突触后密度;以及突触膜。是质膜的整合成分。是NMDA选择性谷氨酸受体复合物的组成部分。在谷氨酸能突触和平行纤维到蒲肯野细胞突触中是活跃的。是突前膜的整合成分。用于研究高同型半胱氨酸血症。认知障碍;胎盘功能不足;和癫痫状态的标志物。这个基因的人类同源物与亨廷顿病;双相障碍;和精神分裂症有关。与人类GRIN2A(谷氨酸离子型受体NMDA型亚单位2A)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
16
423580 bp
165.47
13
27

Grin2a Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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