Grik5 - glutamate ionotropic receptor kainate type subunit 5

Enables identical protein binding activity; kainate selective glutamate receptor activity; and protein domain specific binding activity. Involved in several processes, including cellular response to glucose stimulus; positive regulation of neuron apoptotic process; and protein retention in ER lumen. Located in several cellular components, including perikaryon; postsynaptic density; and terminal bouton. Part of ionotropic glutamate receptor complex. Is active in glutamatergic synapse. Is integral component of postsynaptic membrane and integral component of presynaptic membrane. Used to study visual epilepsy. Biomarker of temporal lobe epilepsy. Orthologous to human GRIK5 (glutamate ionotropic receptor kainate type subunit 5). [provided by Alliance of Genome Resources, Apr 2022]