Enables several functions, including enzyme binding activity; transmembrane transporter binding activity; and type 3 metabotropic glutamate receptor binding activity. Involved in several processes, including activation of adenylate cyclase activity; regulation of calcium ion transmembrane transporter activity; and regulation of vesicle-mediated transport. Located in several cellular components, including growth cone; myelin sheath; and nucleus. Colocalizes with mitochondrial membrane and synaptic vesicle membrane. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in catecholaminergic polymorphic ventricular tachycardia 4; long QT syndrome 14; and long QT syndrome 15. Orthologous to several human genes including CALM1 (calmodulin 1). [provided by Alliance of Genome Resources, Apr 2022]