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中文小鼠
Pde5a - phosphodiesterase 5A, cGMP-specific
Alias:
Cn5n
Pde5
Cgbpde
PDE5a2
Pde5a1
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激活3',5'-环核苷酸磷酸二酯酶活性和cGMP结合活性。参与MAP激酶活性的正向调节；肌肉系统过程的调节；以及心肌的松弛。在几个过程的上游或内部发挥作用，包括cGMP分解过程；T细胞增殖的负向调节；以及卵母细胞发育的正向调节。预测位于细胞质中。在几个结构中表达，包括消化系统；大脑；生殖泌尿系统；呼吸系统；和感觉器官。这个基因的人类正交对(s)涉及IgA系膜肾炎。与人类PDE5A(磷酸二酯酶5A)正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Pde5a Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
