Adra2c - adrenoceptor alpha 2C

Predicted to enable several functions, including alpha-2A adrenergic receptor binding activity; alpha2-adrenergic receptor activity; and protein dimerization activity. Involved in several processes, including negative regulation of uterine smooth muscle contraction; positive regulation of vasoconstriction; and regulation of sensory perception of pain. Located in axon terminus and neuronal cell body. Is active in glutamatergic synapse. Is integral component of postsynaptic density membrane. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human ADRA2C (adrenoceptor alpha 2C). [provided by Alliance of Genome Resources, Apr 2022]