Pde11a - phosphodiesterase 11A

Predicted to enable cGMP binding activity and cGMP-stimulated cyclic-nucleotide phosphodiesterase activity. Predicted to be involved in negative regulation of cAMP-mediated signaling; negative regulation of cGMP-mediated signaling; and signal transduction. Predicted to be located in perikaryon. Is expressed in axial skeleton and nervous system. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease. Orthologous to human PDE11A (phosphodiesterase 11A). [provided by Alliance of Genome Resources, Apr 2022]