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中文人类
ALOX5AP - Arachidonate 5-lipoxygenase Activating Protein
Alias:
FLAP
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这个基因编码一个蛋白质，与5-脂氧合酶一起，是白细胞三烯合成所必需的。白细胞三烯是花生四烯酸的代谢产物，与各种类型的炎症反应有关，包括哮喘、关节炎和银屑病。这个蛋白质定位在质膜上。抑制其功能可以阻止5-脂氧合酶从细胞质向细胞膜的移动，并抑制5-脂氧合酶的激活。已经发现了这个基因的不同剪接转录变异体，它们编码不同的异构体。[RefSeq，2011年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ALOX5AP Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
