Enables lipid kinase activity. Acts upstream of or within several processes, including autophagosome organization; phosphatidylinositol-3-phosphate biosynthetic process; and protein kinase B signaling. Located in endocytic vesicle. Is expressed in eye; limb; nervous system; and skeleton. Orthologous to human PIK3C2B (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta). [provided by Alliance of Genome Resources, Apr 2022]