小鼠

Nr0b2 - nuclear receptor subfamily 0, group B, member 2

Alias:
SHP
Shp1
SHP-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个核激素受体家族的蛋白质成员。编码的孤儿受体缺乏DNA结合域,但通过与其他激素受体相互作用,以竞争性抑制共激活子的结合,同时也作为转录核心抑制子来调节基因表达。编码的受体可能调节胆汁酸合成和雄性的性成熟。同源性敲除小鼠表现出胆汁酸积累,低密度脂蛋白胆固醇(LDL-C)水平降低,并且在雄性小鼠中,睾丸成熟时间较早。[RefSeq,2015年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
2
3311 bp
28.76
11
9

Nr0b2 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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