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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Nr0b2 - nuclear receptor subfamily 0, group B, member 2
Alias:
SHP
Shp1
SHP-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个核激素受体家族的蛋白质成员。编码的孤儿受体缺乏DNA结合域,但通过与其他激素受体相互作用,以竞争性抑制共激活子的结合,同时也作为转录核心抑制子来调节基因表达。编码的受体可能调节胆汁酸合成和雄性的性成熟。同源性敲除小鼠表现出胆汁酸积累,低密度脂蛋白胆固醇(LDL-C)水平降低,并且在雄性小鼠中,睾丸成熟时间较早。[RefSeq,2015年8月提供]
Related ID:
NCBI:23957
ENSEMBL:ENSMUSG00000037583
UNIPROT:Q62227
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
23957
1
2
3311 bp
28.76
11
9
Nr0b2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Type
Name
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