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中文小鼠
Mmp17 - matrix metallopeptidase 17
Alias:
MT4MMP
MTMMP4
MT4-MMP
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这个基因编码一个属于基质金属蛋白酶家族的成员，这个家族的酶可以降解细胞外基质，参与组织重塑、伤口修复、动脉粥样硬化进展和肿瘤侵袭。编码的前原蛋白经过蛋白水解加工，生成一个成熟的、依赖锌的内肽酶。缺乏编码蛋白的小鼠血管平滑肌细胞功能紊乱，血管壁的细胞外基质改变，导致对血管紧张素II诱导的胸主动脉瘤的易感性增加。[RefSeq，2016年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Mmp17 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
