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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ALOX12 - Arachidonate 12-lipoxygenase, 12S Type
Alias:
LOG12
12-LOX
12S-LOX
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码脂氧合酶家族的一员。编码的酶作用于不同的多不饱和脂肪酸底物,生成生物活性脂质介质,包括类二十烷酸和脂质素。编码的酶及其反应产物已被证明可以调节血小板功能。这个基因在来自糖尿病患者的人胰腺胰岛中的表达升高。这个基因的等位基因变异可能与弓形虫感染易感性有关。这个基因的多个假基因已经在人类基因组中被发现。[由RefSeq,2017年8月提供]
Related ID:
NCBI:239
ENSEMBL:ENSG00000108839
HGNC:429
UNIPROT:P18054
OMIM:152391
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
239
2
14
14706 bp
75.69
52
--
5
28
ALOX12 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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