Arih2 - ariadne RBR E3 ubiquitin protein ligase 2

Predicted to enable ubiquitin conjugating enzyme binding activity and ubiquitin protein ligase activity. Acts upstream of or within ubiquitin-dependent protein catabolic process. Predicted to be located in nucleoplasm. Predicted to be part of Cul5-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system; and nervous system. Orthologous to human ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2). [provided by Alliance of Genome Resources, Apr 2022]