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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Apob - apolipoprotein B
Alias:
apob-48
apob-100
Apo B-100
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因产物是乳糜微粒和低密度脂蛋白的主要载脂蛋白。它在血浆中以两种主要异构体存在,即apoB-48和apoB-100。与人类中的apoB-48和apoB-100结构等同物不同,后者分别专在于肠道和肝脏中合成,小鼠的apoB-48异构体也在小鼠肝脏中发现。apoB的肠道和肝脏形式由单个非常长的mRNA的一个单一基因编码。两种异构体共享一个共同的N端序列。较短的apoB-48蛋白是在apoB-100转录本的残基2179处(CAA->UAA)的RNA编辑后产生的,从而产生了终止密码子,并导致早期翻译终止。[由RefSeq,2008年7月提供]
Related ID:
NCBI:238055
ENSEMBL:ENSMUSG00000020609
UNIPROT:E9Q414
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
238055
2
29
39211 bp
509.43
13
8
Apob Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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