小鼠

Adamts5 - a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)

Alias:
ADMP-2
ASMP-2
ADAMTS1
ADAM-TS5
ADAMTS11
9530092O11Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个属于“去整合素和金属蛋白酶含血栓素主题模式”(ADAMTS)家族的多结构域基质相关金属内肽酶,这些酶在组织形态发生和病理生理重塑、炎症和血管生物学中具有多种作用。编码的前原原蛋白经历蛋白水解加工,产生一种活性、锌依赖的聚集蛋白酶酶。缺乏编码的蛋白质的小鼠对手术诱导的骨关节炎和抗原诱导的关节炎有保护作用。[RefSeq,2016年5月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
8
42969 bp
101.84
10
12

Adamts5 Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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