人类

FLRT2 - Fibronectin Leucine Rich Transmembrane Protein 2

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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码纤维连接蛋白富含亮氨酸的跨膜(FLRT)家族的一员,该家族调节早期胚胎血管和神经发育。编码的I型跨膜蛋白具有一个细胞外区域,该区域由N-端富含亮氨酸的重复结构域和3型纤维连接蛋白结构域组成,后面是一个跨膜结构域和一个短的C-端细胞质尾结构域。它既作为同亲性细胞粘附分子又作为异亲性化学排斥剂发挥作用,通过与Uncoordinated-5受体家族的成员相互作用。蛋白水解去除细胞外区域控制发育中神经元的迁移。可选剪接产生多个转录变异体。[由RefSeq,2016年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6
2
124285 bp
74.05
28
--
9
6

FLRT2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
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Comparison
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