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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
IL17RA - Interleukin 17 Receptor A
Alias:
CD217
IL17R
IMD51
CANDF5
CDw217
IL-17RA
hIL-17R
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
白介素17A(IL17A)是一种由激活的T淋巴细胞分泌的促炎细胞因子。它可以有效诱导CD34阳性造血前体成熟为中性粒细胞。这个基因编码的跨膜蛋白(白介素17A受体;IL17RA)是一种普遍存在的I型膜糖蛋白,与白介素17A具有低亲和力。白介素17A及其受体在许多炎症和自身免疫疾病(如类风湿性关节炎)中发挥着病理性作用。与其他细胞因子受体一样,这个受体可能具有多聚体结构。选择性剪接导致多个转录变异体,编码不同的异构体。[RefSeq,2014年2月提供]
Related ID:
NCBI:23765
ENSEMBL:ENSG00000177663
HGNC:5985
UNIPROT:Q96F46
OMIM:605461
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
23765
2
13
30694 bp
96.12
806
2
14
18
IL17RA Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
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Protein
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No data available
* This data comes from NCBI.
Gene Expression
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