人类

IL17RA - Interleukin 17 Receptor A

Alias:
CD217
IL17R
IMD51
CANDF5
CDw217
IL-17RA
hIL-17R
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
白介素17A(IL17A)是一种由激活的T淋巴细胞分泌的促炎细胞因子。它可以有效诱导CD34阳性造血前体成熟为中性粒细胞。这个基因编码的跨膜蛋白(白介素17A受体;IL17RA)是一种普遍存在的I型膜糖蛋白,与白介素17A具有低亲和力。白介素17A及其受体在许多炎症和自身免疫疾病(如类风湿性关节炎)中发挥着病理性作用。与其他细胞因子受体一样,这个受体可能具有多聚体结构。选择性剪接导致多个转录变异体,编码不同的异构体。[RefSeq,2014年2月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2
13
30694 bp
96.12
806
2
14
18

IL17RA Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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