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中文人类
SLC7A11 - Solute Carrier Family 7 Member 11
Alias:
xCT
CCBR1
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这个基因编码一个异质、非钠依赖的阴离子氨基酸转运系统成员，对半胱氨酸和谷氨酸具有高度特异性。在这个系统中，被指定为Xc(-)的半胱氨酸阴离子形式与谷氨酸交换运输。这种蛋白质已被鉴定为卡波西肉瘤相关疱疹病毒融合和进入细胞的主要调节因子。此外，原发性胶质瘤中该基因的表达增加（与正常脑组织相比）与通过XCT通道增加谷氨酸分泌有关，导致神经元细胞死亡。[RefSeq，2011年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SLC7A11 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
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CAS Number
Status
Phase
Link
References Literature
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PMID
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Year
IF
