人类

KPNA6 - Karyopherin Subunit Alpha 6

Alias:
IPOA7
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
核质运输,是一个信号和能量依赖的过程,通过核膜上的核孔复合体进行。含有核定位信号(NLS)的蛋白质的进口需要NLS进口受体,这是一个由导入蛋白α和β亚基组成的异二聚体,也称为核搬运蛋白。导入蛋白α在细胞质中结合含有NLS的货物,导入蛋白β将复合物对接在核孔复合体的胞质侧。在核苷三磷酸和小GTP结合蛋白Ran的存在下,复合物进入核孔复合体,导入蛋白亚基解离。导入蛋白α与它的乘客蛋白进入核质,导入蛋白β留在孔上。这个基因编码的蛋白质是导入蛋白α家族的成员。[由RefSeq提供,2008年7月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
14
68508 bp
60.03
5
--
6
12

KPNA6 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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