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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
SPO11 - SPO11 Initiator Of Meiotic Double Strand Breaks
Alias:
CT35
TOPVIA
SPATA43
TOPOVIA
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
减数分裂重组和染色体分离需要在配对染色体同源中形成双链断裂(DSBs)。在酵母的减数分裂过程中,一种减数分裂重组蛋白与DSBs的5'端共价连接,对DSBs的形成是必需的。这个基因编码的蛋白质在序列和保守特征上与酵母的减数分裂重组蛋白相似。这个蛋白质属于TOP6A蛋白家族。已经发现这个基因有几个编码不同异型的转录变异体,但只有两个它们的完整长度已经被描述。[由RefSeq,2008年7月提供]
Related ID:
NCBI:23626
ENSEMBL:ENSG00000054796
HGNC:11250
UNIPROT:Q9Y5K1
OMIM:605114
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
23626
8
13
14191 bp
44.54
13
--
14
4
SPO11 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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