人类

SPO11 - SPO11 Initiator Of Meiotic Double Strand Breaks

Alias:
CT35
TOPVIA
SPATA43
TOPOVIA
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
减数分裂重组和染色体分离需要在配对染色体同源中形成双链断裂(DSBs)。在酵母的减数分裂过程中,一种减数分裂重组蛋白与DSBs的5'端共价连接,对DSBs的形成是必需的。这个基因编码的蛋白质在序列和保守特征上与酵母的减数分裂重组蛋白相似。这个蛋白质属于TOP6A蛋白家族。已经发现这个基因有几个编码不同异型的转录变异体,但只有两个它们的完整长度已经被描述。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8
13
14191 bp
44.54
13
--
14
4

SPO11 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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