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中文人类
RIGI - RNA Sensor RIG-I
Alias:
RIG1
DDX58
RIG-I
RLR-1
SGMRT2
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DEAD盒蛋白，以其保守基序Asp-Glu-Ala-Asp(DEAD)为特征，是推测的RNA解旋酶，参与许多涉及RNA结合和RNA二级结构改变的细胞过程。该基因编码一个包含RNA解旋酶-DEAD盒蛋白基序和胱天蛋白酶招募结构域(CARD)的蛋白质。它参与病毒双链(ds)RNA的识别和抗病毒先天免疫应答的调节。该基因的突变与Singleton-Merten综合征2有关。[RefSeq，2020年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
RIGI Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
