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中文人类
CCNDBP1 - Cyclin D1 Binding Protein 1
Alias:
HHM
DIP1
GCIP
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这个基因通过其基因产物与Grap2相互作用而被鉴定，Grap2是白细胞特异性的适配器蛋白，对免疫细胞信号传导非常重要。这个基因编码的蛋白质被证明与细胞周期蛋白D相互作用。据报道，将此基因转染到细胞中可以减少Rb基因产物被细胞周期蛋白D依赖性蛋白激酶磷酸化，并抑制E2F1介导的转录活性。该蛋白质还被发现与螺旋-环-螺旋蛋白E12相互作用，被认为是一种肝脏特异性基因表达的负调控因子。已经为这个基因发现了几种可变剪接的变异体。[由RefSeq，2009年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CCNDBP1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
