Plxnb1 - plexin B1

Enables GTPase activating protein binding activity and semaphorin receptor activity. Involved in several processes, including negative regulation of osteoblast proliferation; nervous system development; and positive regulation of phosphatidylinositol 3-kinase signaling. Acts upstream of or within positive regulation of axonogenesis. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of semaphorin receptor complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human PLXNB1 (plexin B1). [provided by Alliance of Genome Resources, Apr 2022]