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中文人类
GTPBP4 - GTP Binding Protein 4
Alias:
NGB
CRFG
NOG1
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GTP结合蛋白是GTP酶，作为分子开关，可以在结合GTP的活性状态和结合GDP的无活性状态之间翻转。在这种情况下，“活性”通常意味着分子作为信号，触发细胞中的其他事件。当细胞外的配体结合到G蛋白连接的受体上时，受体改变其构象，并通过导致它们抛弃GDP并用GTP替换它来开启与其关联的三聚G蛋白。当G蛋白水解其自身结合的GTP，将其转回为GDP时，开关被关闭。但在那之前，活性蛋白有机会从受体扩散开，并将其消息传递给其下游靶标，持续较长时间。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GTPBP4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
