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中文小鼠
Usp3 - ubiquitin specific peptidase 3
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这个基因编码的蛋白质是一种与染色质相关的组蛋白2A和2B去泛素化酶，负调控DNA损伤反应。缺乏这种酶的小鼠造血干细胞储备减少，表明在造血干细胞稳态中具有重要作用。此外，蛋白质水平的敲除导致自发肿瘤发展和寿命缩短，这与保持染色体完整性中的功能一致。可变剪接导致多个转录变异体，编码不同的异构体。[由RefSeq，2014年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Usp3 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
