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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Scn3b - sodium channel, voltage-gated, type III, beta
Alias:
Scnb3
1110001K16Rik
4833414B02Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质参与心肌细胞动作电位中的跨膜转运蛋白结合活性和电压门控钠通道活性该蛋白质涉及窦房结细胞动作电位、正调心率以及调控心房心肌细胞膜的去极化它位于Z带,在心传导和心室心肌细胞动作电位中起到上游或内部调控作用该基因在多个组织中表达,包括肠道、神经系统、感觉器官、骨骼肌和泌尿系统该基因的人类同源物与布格达综合症7有关该基因与人类SCN3B(钠电压门控通道β亚基3)具有同源性[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:235281
ENSEMBL:ENSMUSG00000049281
UNIPROT:Q8BHK2
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
235281
4
7
22403 bp
24.79
4
4
Scn3b Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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