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中文人类
HAAO - 3-hydroxyanthranilate 3,4-dioxygenase
Alias:
HAO
3-HAO
VCRL1
h3HAO
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3-羟基邻氨基苯酸3,4-二加氧酶是一种单体的胞质蛋白，属于内含非血红素亚铁的分子内二加氧酶家族。它广泛分布在周围器官中，如肝和肾，也在中枢神经系统中以较低的量存在。HAAO催化从3-羟基邻氨基苯酸合成喹林酸（QUIN）。QUIN是一种兴奋毒素，其毒性是通过激活谷氨酸N-甲基-D-天门冬氨酸受体介导的。脑内QUIN水平增加可能参与神经和炎症疾病的病理生理。HAAO被认为与QUIN组织水平改变相关的疾病有关。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HAAO Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
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Mutations
Transcripts & Proteins
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Tile View
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
Alphabetical
Cell-specific RNA expression
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Abundance
Alphabetical
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Regulation
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References Literature
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