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中文人类
BRD4 - Bromodomain Containing 4
Alias:
CAP
MCAP
HUNK1
HUNKI
FSHRG4
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这个基因编码的蛋白质与鼠蛋白MCAP同源，MCAP在有丝分裂过程中与染色体结合，并与人类RING3蛋白质，一个丝氨酸/苏氨酸激酶结合。这些蛋白质中的每一个都含有两个bromodomains，这是一个保守的序列基序，可能涉及染色质定位。这个基因被认为是染色体19的易位t(15;19)(q13;p13.1)的靶点，这定义了年轻人的上呼吸道癌。已经描述了两个可变剪接转录变异体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
BRD4 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
