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中文人类
TARDBP - TAR DNA Binding Protein
Alias:
ALS10
TDP-43
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HIV-1，获得性免疫缺陷综合症（AIDS）的致病因素，包含一个在复制周期中产生染色体整合DNA的RNA基因组。转录激活因子Tat激活HIV-1基因表达依赖于位于转录起始点下游的RNA调节元件（TAR）。这个基因编码的蛋白质是一个转录抑制剂，能与染色体整合的TAR DNA结合并抑制HIV-1转录。此外，这个蛋白质还调节CFTR基因的可变剪接。20号染色体上存在一个类似的假基因。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TARDBP Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
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PMID
Journal
Year
IF
