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中文人类
ITGB3BP - Integrin Subunit Beta 3 Binding Protein
Alias:
CENPR
NRIF3
TAP20
CENP-R
HSU37139
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这个基因编码一个结合并增强核受体家族成员活性的转录协同调节子，包括甲状腺激素受体和类视黄酸X受体。这个蛋白质也作为NF-kappaB依赖信号传导的核心抑制子。这个蛋白质通过caspase 2介导的信号通路在乳腺癌细胞中诱导凋亡。这个蛋白质也是着丝粒特异性的组蛋白H3变异体核小体相关复合物（CENP-NAC）的成分，可能通过将组蛋白H3变异体CENP-A招募到着丝粒来参与有丝分裂进程。交替剪接产生多个转录变异体。[RefSeq，2011年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ITGB3BP Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
