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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
SIRT3 - Sirtuin 3
Alias:
SIR2L3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
SIRT3编码一个III类组蛋白脱乙酰基酶的sirtuin家族成员,与酵母Sir2蛋白同源。编码的蛋白质仅在线粒体中发现,它可以消除活性氧物种,抑制凋亡,并防止癌细胞的形成。SIRT3对核基因表达、癌症、心血管疾病、神经保护作用、衰老和代谢控制具有广泛的影响。[由RefSeq,2019年5月提供]
Related ID:
NCBI:23410
ENSEMBL:ENSG00000142082
HGNC:14931
UNIPROT:Q9NTG7
OMIM:604481
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
23410
20
7
21902 bp
43.57
21
--
14
23
SIRT3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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