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中文人类
SIRT5 - Sirtuin 5
Alias:
SIR2L5
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这个基因编码一个Sirtuin家族蛋白质成员，与酵母Sir2蛋白同源。Sirtuin家族的成员以其sirtuin核心结构域为特征，分为四个类别。人类sirtuin的功能尚未确定；然而，酵母sirtuin蛋白已知调节表观遗传基因沉默并抑制rDNA的重组。研究表明，人类sirtuins可能作为具有单ADP核糖基转移酶活性的细胞内调节蛋白发挥作用。这个基因编码的蛋白质属于sirtuin家族的第三类。这个基因的可变剪接导致多个转录变异体。[RefSeq，2010年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SIRT5 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
