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中文人类
ARHGEF18 - Rho/Rac Guanine Nucleotide Exchange Factor 18
Alias:
RP78
SA-RhoGEF
p114RhoGEF
P114-RhoGEF
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罗戈蛋白是调节细胞多种功能的GTP结合蛋白，包括细胞骨架重排、基因转录、细胞生长和迁移。Rho GTPases的激活直接受鸟苷酸交换因子（GEFs）的控制。这个基因编码的蛋白质是一种鸟苷酸交换因子，属于Rho GTPase GEF家族。家庭成员具有一个共同的特征，一个Dbl（DH）同源结构域，后面跟着一个pleckstrin（PH）同源结构域。已经发现了编码不同异构体的可变剪接转录变异体。[RefSeq，2018年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ARHGEF18 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
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Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
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Name
MGI
Strain of Origin
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Mutations
Related Drugs
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CAS Number
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Phase
Link
References Literature
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Year
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