人类

FN1 - Fibronectin 1

Alias:
FN
CIG
FNZ
MSF
ED-B
FINC
GFND
LETS
GFND2
SMDCF
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码纤连蛋白,它是一种存在于血浆中的可溶性二聚体形式的糖蛋白,以及在细胞表面和细胞外基质中的二聚体或多聚体形式。编码的前原蛋白在蛋白水解过程中被加工成成熟蛋白。纤连蛋白参与细胞粘附和迁移过程,包括胚胎发生、伤口愈合、血液凝固、宿主防御和转移。该基因有三个区域可发生可选的剪接,具有产生20种不同转录变异体的潜力,其中至少有一种编码经历蛋白水解过程的异构体。一些变异体的完整长度尚未确定。[由RefSeq,2016年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
18
46
75204 bp
272.32
1057
2
16
82

FN1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
Al agent
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