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Picalm - phosphatidylinositol binding clathrin assembly protein

Alias:
CALM
CLTH
fit1
fit-1
PAP180
mKIAA4114
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能激活几个功能,包括SH3结构域结合活性;clathrin重链结合活性;和磷脂酰肌醇结合活性。参与几个过程,包括通过转运体内清除淀粉样-β;神经元突起形态发生;和调节淀粉样前体蛋白的分解代谢过程。位于clathrin包被的坑和囊泡中。与细胞质核周区域共定位。在几个结构中表达,包括主动脉;心脏;血淋巴系统腺体;肝脏;和肺。这个基因的人类同源物与急性粒细胞白血病有关。与人类PCALM(磷脂酰肌醇结合的clathrin组装蛋白)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
21
21
79238 bp
71.54
10
13

Picalm Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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