人类

FBXW11 - F-box And WD Repeat Domain Containing 11

Alias:
Hos
BTRC2
FBW1B
Fbw11
BTRCP2
FBXW1B
NEDJED
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码F-box蛋白家族的一员,其特征是一个大约40个氨基酸的基序,即F-box。F-box蛋白构成了泛蛋白酶体复合物的四个亚基之一,称为SCFs(SKP1-cullin-F-box),其功能在于磷酸化依赖性的泛蛋白酶化。F-box蛋白分为三类:包含WD-40结构的Fbws类,包含富亮氨酸重复序列的Fbls类,以及包含不同蛋白质-蛋白质相互作用模块或无明显识别基序的Fbxs类。这个基因编码的蛋白质属于Fbws类,除了一个F-box外,还包含多个WD40重复序列。这个基因包含至少14个外显子,其替代剪接产生了三种转录变异体,它们在是否存在两个替代外显子上有所不同。[RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
13
14
145090 bp
62.09
47
2
9
29

FBXW11 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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