人类

FMO2 - Flavin Containing Dimethylaniline Monoxygenase 2

Alias:
FMO1B1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种含有黄素的单加氧酶家族成员。它是一种依赖NADPH的酶,通过N-羟胺中间体催化一些伯烷基胺的N-氧化。然而,一些人类群体含有具有提前终止密码子的等位基因(FMO2*2A),导致C-末端截短的蛋白质,没有催化活性,并且可能迅速降解。这个基因在染色体1上与其他相关家族成员形成一个簇。可选的剪接导致多个转录变异体。[RefSeq,2014年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
9
27479 bp
60.91
24
--
5
11

FMO2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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