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中文人类
FMO1 - Flavin Containing Dimethylaniline Monoxygenase 1
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代谢N-氧化饮食来源的氨基酸-三甲基胺(TMA)是由含黄素单加氧酶介导的，并在人类中受到遗传FMO3多态性的影响，导致一小部分人群TMA N-氧化能力降低，导致鱼腥味综合征-三甲基胺尿症。该酶的三种形式，即在胎儿肝脏中发现的FMO1，在成人肝脏中发现的FMO2，以及由位于1q23-q25区域的基因簇编码的FMO3，已被发现。含黄素单加氧酶是依赖NADPH的黄酶，催化药物、农药和异源物质的软亲电性杂原子中心的氧化。已发现该基因的不同转录变异体编码不同的异构体。[RefSeq，2013年9月提供]
Basic Information
NCBI
Transcripts
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FMO1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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References Literature
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