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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Wnk1 - WNK lysine deficient protein kinase 1
Alias:
Hsn2
Prkwnk1
EG406236
mKIAA0344
6430573H23Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活蛋白质丝氨酸/苏氨酸激酶活性。参与几个过程,包括细胞表面受体信号通路;淋巴细胞迁移到淋巴结;和肽基丝氨酸磷酸化。在几个过程的上游发挥作用,包括GTP酶活性的负调控;胰腺汁分泌的负调控;和全身动脉血压的正调控。位于细胞质中。在几个结构中表达,包括消化系统;生殖泌尿系统;整合被表皮系统;神经系统;和感觉器官。这个基因的人类同源物与遗传性感觉和自主神经病变2A;遗传性感觉神经病变;高血压;和假性醛固酮减少症有关。与人类WNK1(WNK赖氨酸缺陷蛋白激酶1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:232341
ENSEMBL:ENSMUSG00000045962
UNIPROT:P83741
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
232341
35
28
114730 bp
250.93
10
18
Wnk1 Genetics information (-)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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