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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Iqsec1 - IQ motif and Sec7 domain 1
Alias:
BRAG2
cI-43
D6Ertd349e
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活蛋白激酶结合活性。参与几个过程,包括聚焦粘附解除的正调控;角质细胞迁移的正调控;以及突触后神经递质受体内化的调控。位于Schaffer collateral - CA1突触中。在谷氨酸能突触和突触后密度,细胞内成分中是活跃的。在中枢神经系统;前肢肌肉;感觉器官;和头盖骨中表达。这个基因的人类同源物与智力发育障碍,矮小和行为异常有关。与人类IQSEC1(IQ模序和Sec7结构域ArfGEF 1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:232227
ENSEMBL:ENSMUSG00000034312
UNIPROT:Q8R0S2
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
232227
29
14
329189 bp
108.02
3
10
Iqsec1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Acting
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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