人类

SULF1 - Sulfatase 1

Alias:
SULF-1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种细胞外肝素硫酸酶。编码的酶有选择地从肝素硫酸蛋白聚糖(HSPGs)的肝素硫酸链中去除6-O-硫酸基团。该酶通过高尔基体分泌,并随后定位到细胞表面。这个基因的表达在几种癌症中可能下调,包括肝细胞癌(HCC)、卵巢癌和乳腺癌。可变剪接导致多个转录变异体。[RefSeq,2013年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
29
23
194132 bp
101.03
213
--
10
5

SULF1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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