人类

ATG4B - Autophagy Related 4B Cysteine Peptidase

Alias:
APG4B
AUTL1
HsAPG4B
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
自噬是一种细胞内的内源性蛋白质和受损细胞器被破坏的过程。自噬被认为对细胞的稳态和分化、形态发生、非凋亡性死亡和衰老过程中的细胞重塑是必不可少的。一些恶性肿瘤中自噬水平降低,自噬在控制与癌症相关的无调控细胞生长中的作用已被提出。这个基因编码自噬蛋白家族的一员。编码的蛋白质也被指定为半胱氨酸蛋白酶C-54家族的成员。已经表征了编码不同异型体的替代转录剪接变异体。[RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
8
13
36165 bp
44.29
26
--
7
44

ATG4B Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
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