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中文人类
MAPK8IP3 - Mitogen-activated Protein Kinase 8 Interacting Protein 3
Alias:
syd
JIP3
SYD2
JIP-3
JSAP1
NEDBA
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这个基因编码的蛋白质与果蝇syd基因的产物相似，kinesin I与轴突货物的功能相互作用是必需的。小鼠中类似基因的研究提示，这个蛋白质可能与多种JNK信号通路蛋白激酶相互作用并调节其活性，从而在神经元细胞中作为支架蛋白发挥作用。这个基因的线虫对应物发现可以整合JNK信号和kinesin-1运输来调节突触囊泡的运输。已经描述了这个基因的几个可变剪接转录变异体，但其中一些变异体的完整长度尚未确定。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MAPK8IP3 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
