人类

SNX13 - Sorting Nexin 13

Alias:
RGS-PX1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个包含PHOX结构域和RGS结构域的蛋白质,属于分类蛋白X (SNX)家族和G蛋白信号调节子(RGS)家族。PHOX结构域是一个磷脂酰肌醇结合结构域,SNX家族成员参与细胞内转运。RGS家族成员作为异源三聚G蛋白的Gα亚基的GTP酶激活蛋白的调节分子。该蛋白质的RGS结构域与Gα(s)相互作用,加速其GTP水解,并减弱Gα(s)介导的信号传导。过表达该蛋白质会延迟表皮生长因子受体的溶酶体降解。由于其双功能作用,该蛋白质可能连接异源三聚G蛋白信号传导和囊泡转运。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
14
26
149734 bp
112.19
40
--
4
6

SNX13 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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