人类

FLI1 - Fli-1 Proto-oncogene, ETS Transcription Factor

Alias:
EWSR2
FLI-1
SIC-1
BDPLT21
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个含有ETS DNA结合结构域的转录因子。该基因可以与染色体22上的Ewing肉瘤基因发生t(11;22)(q24;q12)易位,从而产生一个在大多数Ewing肉瘤病例中存在的融合基因。已经发现了涉及这个基因的急性淋巴细胞性白血病相关t(4;11)(q21;q23)易位。选择性剪接导致多个转录变异体。[RefSeq,2012年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
9
9
127917 bp
50.98
124
7
11
15

FLI1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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