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中文人类
ARHGAP26 - Rho GTPase Activating Protein 26
Alias:
GRAF
GRAF1
OPHN1L
OPHN1L1
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细胞与细胞外基质的相互作用触发整合素细胞表面受体开始调节肌动蛋白细胞骨架组织信号传导。这些级联中涉及的蛋白质之一是聚焦粘附激酶。该基因编码的蛋白质是一种与聚焦粘附激酶结合并调节GTP结合蛋白RhoA和Cdc42活性的GTP酶激活蛋白。该基因的缺陷是导致幼年粒细胞-单核细胞白血病（JMML）的原因。已发现该基因有不同的转录变异体，编码不同的异构体。[RefSeq,2017年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ARHGAP26 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
