Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
人类
SPEN - Spen Family Transcriptional Repressor
Alias:
MINT
SHARP
RATARS
RBM15C
HIAA0929
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种激素诱导的转录抑制因子。这种基因产物通过与其他抑制因子的相互作用、招募参与组蛋白去乙酰化过程的蛋白质或通过隔离转录激活因子来实现转录的抑制。这个基因的产物包含一个羧基末端域,该域允许与其他核心抑制因子蛋白结合。这个域还允许与NuRD复合物的成员相互作用,NuRD复合物是一个包含去乙酰化活性的染色质重塑蛋白复合物。此外,这种抑制因子还包含几个RNA识别模体,这些模体赋予其与一种甾体受体RNA共激活剂结合的能力;这种结合可以调节配体结合和非配体结合的甾体受体的活性。[由RefSeq提供,2008年7月]
Related ID:
NCBI:23013
ENSEMBL:ENSG00000065526
HGNC:17575
UNIPROT:Q96T58
OMIM:613484
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
23013
1
15
92750 bp
402.25
386
2
6
20
SPEN Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top