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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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人类
RAB21 - RAB21, Member RAS Oncogene Family
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因属于Rab家族的单分子GTP酶,参与细胞膜交通的控制。编码的蛋白质通过与其整合素alpha尾部的关联在整合素的靶向交通中发挥作用。因此,该编码蛋白质涉及细胞粘附和迁移的调节。这个基因的表达与神经胶质瘤患者的预后不良相关。这个基因被肿瘤抑制因子miR-200b下调,而miRNA-200b在神经胶质瘤组织中本身也被下调。[由RefSeq,2015年11月提供]
Related ID:
NCBI:23011
ENSEMBL:ENSG00000080371
HGNC:18263
UNIPROT:Q9UL25
OMIM:612398
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
23011
2
7
45424 bp
24.35
7
--
5
16
RAB21 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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