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中文人类
DAAM1 - Dishevelled Associated Activator Of Morphogenesis 1
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细胞运动性、粘附、细胞分裂以及其他细胞皮质功能通过重组的肌动蛋白细胞骨架和几种与这些过程相关的formin同源(FH)蛋白来调节。这个基因编码的蛋白质含有两个FH结构域，并属于一个与细胞极性有关的新FH蛋白质亚家族。小GTP酶Rho是细胞骨架架构的关键调节剂，在发育过程中被Wnt/Fz信号激活，以控制细胞极性和运动。这个基因编码的蛋白质被认为作为Wnt诱导的disheveled(Dvl)-Rho复合物的支架蛋白功能。这个蛋白质还促进新的肌动蛋白丝的成核和伸长，并通过稳定微管来调节细胞生长。可变剪接产生多种编码不同蛋白质的转录变异体。[RefSeq，2012年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DAAM1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
