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中文人类
MAPRE1 - Microtubule Associated Protein RP/EB Family Member 1
Alias:
EB1
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这个基因编码的蛋白质首先通过其与APC蛋白的结合而被识别，APC蛋白在家族性和散发性结肠癌中经常发生突变。该蛋白质定位在微管，特别是在有丝分裂细胞中的生长端。在有丝分裂期间，该蛋白质与中心体和纺锤丝微管相关。该蛋白质还与动力蛋白复合物的成分和细胞质动力蛋白的中介链相关。由于这些关联，认为该蛋白质参与微管结构和染色体稳定的调节。这个基因是RP/EB家族的成员。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MAPRE1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
