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中文人类
SEC31A - SEC31 Homolog A, COPII Coat Complex Component
Alias:
HPBKS
ABP125
ABP130
HSPC275
HSPC334
NEDSOSB
SEC31L1
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这个基因编码的蛋白质与酵母Sec31蛋白质相似，是衣壳蛋白复合物II(COPII)外层层的组成部分。该编码蛋白质参与内质网(ER)的囊泡萌发，并在N端附近含有多个WD重复序列，C端一半富含脯氨酸区域。它与SEC13同源蛋白编码的蛋白质（核孔和COPII衣壳复合物组件）相关联，并参与ER-高尔基体运输。发现这个蛋白质被CUL3-KLHL12单泛素化，以调节COPII衣壳的大小，以适应异常形状的货物。可选剪接产生多种转录变异体，编码不同的异构体。[由RefSeq，2015年12月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SEC31A Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
